Xeomin (incobotulinumtoxin A) is a prescription medicine that is injected into muscles and clinically proven to temporarily improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults. Xeomin is made through a unique manufacturing process that isolates the therapeutic component of the molecule and removes the accessory proteins that don't play an active role in treatment. Xeomin is a highly purified neurotoxin.

In 2010, the FDA approved the use of Xeomin for improving moderate to severe frown lines (also known as glabellar lines) between the eyebrows. The FDA granted approval after clinical trials in the U.S. involving 547 adult patients. The studies concluded this treatment successfully reduced frown lines between the eyebrows.

Frown lines form when facial expressions are made as the muscle under the skin contracts. Over time, as your skin ages, these repeated expressions cause lasting frown lines (permanent wrinkles). Neurotoxins, such as Xeomin, are prescription medications that block the signal that cause these muscle contractions so frown lines are softened.

With Xeomin treatments, wrinkles on the forehead and around the eyes become smoother and the skin above your eyebrows may appear "lifted".  Sagging, wrinkled skin makes a person look tired, but this treatment perks the face up, making it appear more alert and relaxed. The degree of line and wrinkle reduction is related to the severity of the patient's condition and the amount of injection used during treatment. Treatment lasts 3-6 months.